Navigating a Case of Treatment-Resistant Depression (TRD) in Clinical Practice
Posted on: July 18, 2022
Last Updated: December 28, 2022
The term treatment-resistant depression (TRD) is problematic because it has been associated with a narrow focus on pharmacotherapeutic non-response and also because it invokes a nihilistic view regarding managing depression.
To overcome these problems the term difficult-to-treat depression (DTD) has been proposed with two main advantages,
- ‘Difficult to treat’ suggests that the management of the depressive illness is likely to be challenging, but at the same time, it is not unachievable.
- The definition of DTD is not predicated on pharmacotherapy alone, and the management of DTD involves a much broader set of strategies – including, for example, psychosocial measures.
This video covers the following:
- Difference between Treatment-resistant depression and Difficult to treat depression
- Navigating a clinical case of TRD / DTD by using the diagnostic hierarchy
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