Key Differences Between High Frequency & Low Frequency rTMS Protocols – Dr. Martjin Arns

Posted on February 13, 2019

Dr Sanil Rege, Consultant Psychiatrist and Founder of Psych Scene and Psych Scene Hub speaks to Dr. Martijn Arns, Chief Scientific Adviser, neuroCare Group; Founding Director & Senior Researcher at Research Institute Brainclinics.

Author Quote :

There are some newer protocols coming along as well. There’s one interesting protocol called ‘intermittent Theta Burst Stimulation (iTBS) ’…What they’ve recently demonstrated and got FDA approved as well, is that they can now do a 3-minute TMS protocol that has a similar efficacy relative to a 20-minute 10 Hz protocol, which I think opens up many avenues for further research…

Take Home Messages :

  1. Remission and response rates remain consistent, regardless of the level of rTMS stimulation applied.
  2. 1 Hz and 10 Hz protocols are used to stimulate the right and left sides of the brain respectively, when treating depression, although 1 Hz bilateral treatment has recently shown to be beneficial for patients.
  3. 1 Hz stimulation is considered to be the safest protocol and better tolerated by patients.



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