In this video, Dr Sanil Rege, consultant psychiatrist reviews the key clinical data for intranasal esketamine in the management of treatment-resistant depression including:

• the onset of action and impact on depression symptoms 24 hours after dosing
• 28-day response and remission rates
• sustained response and prevention of relapse
• safety and tolerability

Based on data from the TRANSFORM 2 and SUSTAIN 1 and SUSTAIN 2 studies, we discuss what these results contribute to clinical practice for both patients and clinicians.

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