Genetically Guided Prescribing: The Future Arrives- Precision Medicine by Dr Ajeet Singh

Posted on: April 10, 2016
Last Updated: August 20, 2019

Prof Ajeet Singh is an academic private psychiatrist whose research has focused on genetically guided prescribing (pharmacogenetics) of antidepressants, particularly the role of the blood-brain-barrier. Dr Singh is the Founder of CNSDose, an academic member of the Clinical Pharmacogenetics Implementation Consortium (CPIC), and member of the Genetic Tests in Psychiatry Taskforce, International Society of Psychiatric Genetics (ISPG).

Author Quotes  

I don’t see this as something that will disempower medicine, I see it as something that will enable it.

In fact, the stuff that you already know is 95% of what you need to know and it’s whether this new science [precision medicine] will actually enhance what we already do by reducing a little bit of the trial and error in both diagnostics and prescribing.

Summary and slides  

Psychiatrist and pharmacogeneticist, A/Prof Ajeet B Singh has a passionate message to deliver about genetically guided prescribing. In this short clip you will be exposed to the intriguing topic of precision medicine. 

Professor Singh presents this short video excerpt with an overview of his upcoming presentation. He explains why he considers that technological developments in the genomic space will likely place a large part in the clinical lives of GPs in the near future.   

Highlighting how psychiatry might be enhanced by genomic medicine, he encourages clinicians to embrace the subject area in order to provide better outcomes for patients. 

 Professor Singh hopes that after this presentation clinicians will be better able to answer point #1 in the slide above in their own way, i.e. you don’t have to be an expert in genomics to feel confident enough in the clinical space to provide general guidance for patients.   

He concludes this introduction by highlighting how governments are now pushing the area of genomic technology forward at an accelerated pace, as precision medicine might ultimately be one answer to reducing healthcare waste. 

Take- Home Points  

  • Experts should be able to explain difficult concepts clearly. 
  • Genetically-guided healthcare will make doctors more relevant than ever. 
  • The cost of the technology involved has decreased considerably since the first whole genome sequence ($3 million in 2003 vs $1000 in 2016). 


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