Dr Sanil Rege

November 23, 2021

Time to read: 11–14 minutes

Constipation is a common side effect of clozapine and may cause death if severe. Unlike agranulocytosis and myocarditis, clozapine’s effects on bowel ...

 Dr Sanil Rege

October 16, 2021

Time to read: 9 minutes

We previously covered antidepressant withdrawal. Antipsychotic withdrawal can pose similar challenges. Despite the challenges...

 Dr Sanil Rege

September 21, 2021

Time to read: 11–13 minutes

Aripiprazole long-acting injections (LAIs) come in two forms – Abilify Maintena and Aristada. This article covers the psychopharmacology of Aripip...

September 13, 2021

Time to read: 7 minutes

Synaptic pruning is an important developmental process that refines and optimises neuronal transmission. ...

 Dr Sanil Rege

August 14, 2021

Time to read: 5 minutes

Smoking affects Clozapine levels. Re...

 Dr Sanil Rege

April 11, 2021

Time to read: 11–13 minutes

DRUG DESCRIPTION AND STRUCTURE Cariprazine (Vraylar, Reagila) is an atypical antipsychotic approved in September 2015 to treat s...

March 25, 2021

Time to read: 10 minutes

Up to 30% of patients with schizophrenia are classed as non-responders to antipsychotics. ...

 Dr Sanil Rege, Prof David Castle, Prof Nagesh Pai, Dr Frances Dark

February 13, 2021

Time to read: 21–25 minutes

Schizophrenia is a complex, chronic disorder characterised by a constellation of positive and negative symptoms.  While clinical practice and therapeut...

Dr Sanil Rege is a Consultant psychiatrist, founder of Psychscene.com and ...

 Dr Sanil Rege

December 16, 2020

Time to read: 6 minutes

The diagnosis and management of early psychosis can pose specific challenges for clinicians. The presentation of early psychosis is fluid and can...