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  •  Dr Sanil Rege
    July 25, 2022
    Time to read: 17–20 minutes

    Switching or Augmentation Strategies in the Treatment of Major Depressive Disorder – What Does the Evidence Tell Us?

    When patients with Major Depressive Disorder (MDD) don’t respond to medication, clinicians have three options: Increase dose, switch or augment....

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  • July 20, 2022

    Application of Intranasal Esketamine (Spravato) in Clinical Practice – Optimising Patient Outcomes – Discussion with A/Prof Scott and Prof Hickie

    In this video, Dr Sanil Rege, Consultant Psychiatrist and Academic Lead of Psych Scene talks to Prof Ian Hickie and A/Prof Liz...

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  • June 30, 2022

    Agomelatine (Valdoxan) for Generalised Anxiety Disorder – Mechanism of Action

    In this video Dr Sanil Rege, Consultant Psychiatrist covers the mechanism of action of Agomelatine. Agomelatine has recently been TGA approved fo...

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  • June 20, 2022

    Long-Acting Injectable Antipsychotics (LAIs) – What do the RANZCP Guidelines Say?

    Long-acting injectable antipsychotics (LAIs) are an effective treatment option in schizophrenia.  However, they are often viewed negatively by clinicia...

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  •  Dr Sanil Rege
    June 17, 2022
    Time to read: 10 minutes

    Brexpiprazole – Psychopharmacology | Mechanism of Action | Clinical Application

    Brexpiprazole [7-{4-[4-(1-benzothiophene-4-yl) piperazin-1-yl]butoxy}quinolin-2(1H)-one] is a novel atypical antipsychotic that is structurally similar ...

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  •  Dr Sanil Rege
    June 9, 2022
    Time to read: 8 minutes

    New Pharmacological Treatments for Attention Deficit Hyperactivity Disorder (ADHD) – Viloxazine | Azstarys | Mazindol | Centanafadine

    Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterised by inattention, disorganisation, and/or hyperactive impul...

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  •  Dr Sanil Rege
    June 3, 2022
    Time to read: 4 minutes

    Making Sense of Clozapine Levels – Clinical Application | Clozapine – NorClozapine Ratio | Side Effects

    Clozapine is metabolised in the liver predominantly by CYP1A2 and partially (35% ) by CYP3A4. It is, however, important to recognise that in some patien...

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  •  Dr Sanil Rege
    May 30, 2022
    Time to read: 7 minutes

    Lemborexant – Mechanism of Action | Psychopharmacology | Clinical Application

    Lemborexant (DAYVIGO) is a dual orexin receptor antagonist (DORA) that was approved in 2019 for the treatment of sleep-onset and/or sleep maintenance in...

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  •  Dr Sanil Rege
    April 26, 2022
    Time to read: 11–13 minutes

    Review of Lithium-Induced Renal Dysfunction – Pathophysiology | Diagnosis | Management

    Lithium-induced nephropathy has been reported since the 1970s and covers many kidney function impairments. ...

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  •  Dr Sanil Rege, Prof David Castle
    April 7, 2022
    Time to read: 21–25 minutes

    Antipsychotic Induced Weight Gain and Metabolic Dysfunction – A Review of Pathophysiology and Management Strategies

    Obesity is a critical public health problem predictive of the development of cardiovascular disease, metabolic syndrome,...

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LATEST

  • Agomelatine (Valdoxan) for Generalised Anxiety Disorder – Mechanism of Action

    Agomelatine (Valdoxan) for Generalised Anxiety Disorder – Mechanism of Action

    June 30, 2022
  • Psychiatrist Analyzes Psychologist Testimonies in the Amber Heard vs J.Depp trial | Trauma Disorders

    Psychiatrist Analyzes Psychologist Testimonies in the Amber Heard vs J.Depp trial | Trauma Disorders

    June 27, 2022
  • Long-Acting Injectable Antipsychotics (LAIs) – What do the RANZCP Guidelines Say?

    Long-Acting Injectable Antipsychotics (LAIs) – What do the RANZCP Guidelines Say?

    June 20, 2022

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