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  •  Dr Sanil Rege
    January 21, 2023
    Time to read: 8 minutes

    Varenicline (CHAMPIX) – Mechanism of Action | Psychopharmacology | Clinical Application

    Varenicline (CHANTIX /CHAMPIX) is a nicotinic acetylcholine receptor (nAChR) partial agonist indicated as a smoking cessation drug. ...

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  • December 19, 2022
    Time to read: 1 minutes

    Cariprazine Approved by FDA as Adjunctive Treatment for Major Depressive Disorder

    AbbVie announced that the U.S. Food and Drug Administration (FDA) has approved VRAYLAR® (cariprazine) ; (known as Reagila in Australia) as an adjunctiv...

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  •  Dr Sanil Rege
    November 24, 2022
    Time to read: 33–40 minutes

    Primer on Neurobiology and Neuropsychiatry of Sleep – Application to Clinical Practice

    Humans spend 1/3rd of their life sleeping. Sleep is critical to adaptive human functioning with its links to cognition, mood, ...

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  •  Dr Sanil Rege
    October 27, 2022
    Time to read: 10 minutes

    Memantine – Mechanism of Action | Psychopharmacology | Clinical Application

    Memantine is a low-affinity voltage-dependent non-competitive NMDA receptor antagonist that is approved for treating moderate-...

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  •  Dr Sanil Rege
    September 30, 2022
    Time to read: 16–19 minutes

    Smoking and Schizophrenia – Neurobiology of Nicotine Dependence | Smoking Cessation Treatments

    The interaction between smoking and schizophrenia is complex and multifaceted, with patients consistently showing higher rates...

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  • September 14, 2022

    Neurobiology of Depression and Psychopharmacology of Esketamine – A Novel Rapid-acting Antidepressant

    In this video, Dr Sanil Rege reviews the ...

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  • September 5, 2022

    Agomelatine in Generalised Anxiety Disorder – Insights from Network Meta-analyses and WFSBP Guidelines

    In this video, Dr Sanil Rege explores the use of network meta-analysis to make indirect comparisons between drugs that have not been compared in head-to...

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  •  Dr Sanil Rege
    July 25, 2022
    Time to read: 17–20 minutes

    Switching or Augmentation Strategies in the Treatment of Major Depressive Disorder – What Does the Evidence Tell Us?

    When patients with Major Depressive Disorder (MDD) don’t respond to medication, clinicians have three options: Increase dose, switch or augment....

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  • July 20, 2022

    Application of Intranasal Esketamine (Spravato) in Clinical Practice – Optimising Patient Outcomes – Discussion with A/Prof Scott and Prof Hickie

    In this video, Dr Sanil Rege, Consultant Psychiatrist and Academic Lead of Psych Scene talks to Prof Ian Hickie and A/Prof Liz...

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  • June 30, 2022

    Agomelatine (Valdoxan) for Generalised Anxiety Disorder – Mechanism of Action

    In this video Dr Sanil Rege, Consultant Psychiatrist covers the mechanism of action of Agomelatine. Agomelatine has recently been TGA approved fo...

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