Obsessions: Persistent, unwanted, repetitive, intrusive thoughts, images and urges which are ego-dystonic and cause anxiety and distress Compulsions: Repetitive behaviours or mental acts performed in response to an obsession to reduce the anxiety or distress to prevent a feared consequence. Screening Recently validated screening… Read More »
Prof Michael Berk talks about the application of NAC in addiction, autism, OCD and traumatic brain injury. NAC and Addiction In addiction, you have a situation where glial glutamate uptake is via a transporter called Glutamate Transporter 1 (GLT1) and drug abuse down regulates this… Read More »
Learning Point 1 – The main circuits involved in OCD are the Cortico-thalamic-striatal- cortical loop (CTSC). Overactivation of this ‘worry loop’ is responsible for the development of obsessions. Selective Serotonin Reuptake Inhibitors (SSRI’s) at higher doses are effective in addressing the malfunctioning in this critical… Read More »
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