A conventional, typical or first-generation antipsychotic is defined by the ability to block dopamine (D2) receptors. They also have in, varying degrees, M1, Alpha-1 and H1 receptor blockade. Typical antipsychotics: Chlorpromazine Flupenthixol (depot) Fluphenazine (depot) Haloperidol Sulpiride Trifluoperazine How does dopamine blockade treat psychosis? Blocking… Read More »
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