A Focus on Vortioxetine – Mechanism of Action and Efficacy

Posted on October 27, 2017
Time to read: 5 minutes

Vortioxetine is an atypical antidepressant with multimodal activity. It is a serotonin modulator and stimulator because although it has SERT inhibition properties, it is also a serotonin receptor agonist and antagonist.

It also exerts effects on norepinephrine, dopamine, glutamate, GABA, and the cholinergic system.


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