Obstructive Sleep Apnea and Depression – Pathophysiology & Management
Obstructive sleep apnea (OSA) is a common sleep disorder with a prevalence of approximately 20% in the general population.
OSA is defined as >5 apnea events per hour of sleep with 5-14 apneas classified as mild OSA, 15-29 as moderate OSA and ≥30 as severe OSA.
OSA increases many adverse clinical outcomes. [Punjabi, 2008], [Ejaz et al., 2011]
Schweitzer, P. K., Rosenberg, R., Zammit, G. K., Gotfried, M., Chen, D., Carter, L. P., … & Strohl, K. P. (2019). Solriamfetol for excessive sleepiness in obstructive sleep apnea (TONES 3). A randomized controlled trial. American journal of respiratory and critical care medicine, 199(11), 1421-1431.