Making Sense of Clozapine Levels – Clinical Application | Clozapine – NorClozapine Ratio | Side Effects

Posted on:June 3, 2022
Last Updated: November 27, 2022
Time to read: 4 minutes

Clozapine is metabolised in the liver predominantly by CYP1A2 and partially (35% ) by CYP3A4. It is, however, important to recognise that in some patients, CYP3A4 may be the predominant metabolic pathway. [Polcwiartek & Nielsen, 2016 ]


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