Lithium Induced Hyperparathyroidism – Clinical Features and Management

Posted on:September 6, 2020
Last Updated: October 2, 2020
Time to read: 5 minutes

Lithium is an evidence-based treatment in the acute and maintenance phases of bipolar affective disorder.

It is also an effective augmentation strategy in treatment-resistant depression and has anti-suicidal effects.

But Lithium has significant metabolic and endocrine adverse effects. With regards to the endocrine effects, hypothyroidism is the best recognised.

Another important side-effect is lithium-induced hyperparathyroidism leading to hypercalcaemia, which has a range of psychological and potentially serious physical manifestations.