Lithium Induced Hyperparathyroidism – Clinical Features and Management
It is also an effective augmentation strategy in treatment-resistant depression and has anti-suicidal effects.
But Lithium has significant metabolic and endocrine adverse effects. With regards to the endocrine effects, hypothyroidism is the best recognised.
Another important side-effect is lithium-induced hyperparathyroidism leading to hypercalcaemia, which has a range of psychological and potentially serious physical manifestations.