Inflammation and Depression – A Simplified Guide

Posted on:December 19, 2021
Last Updated: January 4, 2022
Time to read: 12–14 minutes

A novel and emerging framework describes the involvement of inflammation and the immune system in the pathophysiology of depression.

The PATHOS-D hypothesis states that depressive symptoms are components of the immune system that promote pathogen defence. [Raison and Miller, 2013]


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