Anorexia Nervosa – A Review of Neurobiology, Diagnosis and Management

Posted on:February 6, 2021
Last Updated: July 25, 2023
Time to read: 22–27 minutes

Anorexia nervosa (AN) is a serious mental disorder that affects all ages and sexes, however; it is typically found in females (1:8 ratio) of which 95% have late adolescence or early adulthood onset. [Hudson et al. 2007]

Research shows that up to 25% of patients will develop an enduring form of AN and up to one third will continue to experience residual symptoms throughout adulthood.

Anorexia nervosa has the highest mortality rate of any mental health disorder, with an estimated all-cause standardised mortality ratio of 1.7 to 5.9. [Arcelus et al. 2011]

Prevalence of AN is not affected by culture or ethnicity, and genetic factors are considered a major risk factor for developing AN. [Strober et al. 2000]; [Yilmaz et al. 2015]