What are the Mechanisms of Metabolic Syndrome? – Conversations with Dr Stephen Stahl

Posted on January 23, 2017

This interview is the third as part of a series of brief interviews where Dr. Sanil Rege talks to Dr. Stephen Stahl about key issues that face psychiatry and our patients.  Dr. Stahl, MD, is a practicing Psychiatrist in Carlsbad, USA, and author of the best-selling textbook, Essential Psychopharmacology. Dr. Stahl has held faculty positions at Stanford University, the University of California at Los Angeles, the Institute of Psychiatry London, the Institute of Neurology London, and, currently, at the University of California at San Diego.

Take Home Messages

Weight gain is one of the fastest ways to get metabolic syndrome As you get overweight and obese, your triglycerides go up and you get insulin resistance.

There appears to be some (mysterious) receptor driven phenomenon for certain drugs that as soon as you give them – BANG – within days, up goes the triglycerides.

There is a drug-induced insulin resistance independent of weight gain.