Clozapine was first introduced into practice in the 1960’s. However, in 1976, there were reports of fatal agranulocytosis (drastic reduction in white blood cells), which resulted in its complete withdrawal from the market. Then, in 1990, it was again granted approval but only as a… Read More »
The Historical, Clinical and Risk Management – 20 (HCR -20) is a structured tool to assess the risk of violence. The items are below. Historical items H1 Violence As a child (under 12 years) As an adolescent (13-17 years) As an adult (18 and over)… Read More »
In the last decade another neurometabolic disorder has been increasingly recognized as a cause of “secondary” schizophrenia. Niemann-Pick disease type C (NPC) is a recessive neurovisceral disorder affecting intracellular cholesterol trafficking, and occurs in 1:100,000 individuals in a pan ethnic distribution. Dysfunction of the NPC1… Read More »
This interview is the fifth as part of a series of brief interviews where Dr Sanil Rege talks to Dr Stephen Stahl about key issues that face psychiatry and our patients. Dr Stahl, MD, is a practicing Psychiatrist in Carlsbad, USA, and author of the… Read More »
This interview is the fourth as part of a series of brief interviews where Dr Sanil Rege talks to Dr Stephen Stahl about key issues that face psychiatry and our patients. Dr Stahl, MD, is a practising Psychiatrist in Carlsbad, USA, and author of the… Read More »
This longitudinal study involved 56 outpatients (54 with paranoid schizophrenia and 2 with schizoaffective disorder) who had no history of head injuries or neurological conditions. All patients were on a stable dose of antipsychotics and had been for over 2 years. The patients were equally… Read More »
The Hub is a platform to share ideas, cases and concepts that bridge the gap between academia and the real world. Think about it as the real world textbook, a platform rich with experiences. Many fields including medicine and psychiatry suffer from ‘closet’ ideas. Many brilliant solutions, the so called tacit knowledge, is embedded in the brains of people that do not have the platform to express them or at least reach a wider audience. The Hub is a device to unlock this knowledge and share it with the wider world. The Hub gives you an opportunity to make a difference.