A 60-year-old female of European background was admitted to a Neuropsychiatry Unit with a history of sub-acute onset of leg weakness, ataxia, confusion and poor self-care on a background of heavy periods of alcohol intake; drinking up to 4 L of cask wine per day.… Read More »
Professor Michael Berk is currently an NHMRC Senior Principal Research Fellow and is Alfred Deakin Chair of Psychiatry at Deakin University and Barwon Health, where he heads the IMPACT Strategic Research Centre. He also is an Honorary Professorial Research Fellow in the Department of Psychiatry,… Read More »
Graham Hughes trained at The London Hospital. In 1969-70, he spent two years with Professor Charles Christian in New York working on the introduction of anti-DNA assays in lupus. He set up Europe’s first dedicated lupus clinic in 1971 and described the antiphospholipid syndrome (Hughes… Read More »
Learning Point 1 – The main circuits involved in OCD are the Cortico-thalamic-striatal- cortical loop (CTSC). Overactivation of this ‘worry loop’ is responsible for the development of obsessions. Selective Serotonin Reuptake Inhibitors (SSRI’s) at higher doses are effective in addressing the malfunctioning in this critical… Read More »
A 21-year-old female of Maltese background presented with a first episode of mania and was initiated on Risperidone and Sodium Valproate. The dose was increased to a dose of 4 mg /day of Risperidone and 1500 mg /day of Sodium Valproate with minimal response. Two… Read More »
Prof. Graham Hughes trained at the London Hospital and spent two years with Prof. Charles Christian in New York working on the introduction of the anti-DNA assay. He set up Europe’s first dedicated Lupus clinic in 1971 and described the Antiphospholipid syndrome / Hughes Syndrome… Read More »
Missing an autoimmune disease masquerading as a psychiatric disorder can have devastating consequences and in some cases, be fatal. The stark reality of missing such immune manifestations affecting the brain is highlighted in this article . The journalist Susannah Cahalan (see video below) brought this… Read More »
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