A 60-year-old female of European background was admitted to a Neuropsychiatry Unit with a history of sub-acute onset of leg weakness, ataxia, confusion and poor self-care on a background of heavy periods of alcohol intake; drinking up to 4 L of cask wine per day.… Read More »
Learning Point 1 – The main circuits involved in OCD are the Cortico-thalamic-striatal- cortical loop (CTSC). Overactivation of this ‘worry loop’ is responsible for the development of obsessions. Selective Serotonin Reuptake Inhibitors (SSRI’s) at higher doses are effective in addressing the malfunctioning in this critical… Read More »
A 21-year-old female of Maltese background presented with a first episode of mania and was initiated on Risperidone and Sodium Valproate. The dose was increased to a dose of 4 mg /day of Risperidone and 1500 mg /day of Sodium Valproate with minimal response. Two… Read More »
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