The Link between Polycystic Ovarian Syndrome (PCOS) and Psychiatric Disorders – A Mother’s Plea

Posted on March 15, 2016

 

This letter was sent by a concerned mother (permission to share obtained) in response to a previous post on Polycystic Ovarian syndrome (PCOS) and its link to mental health disorders. It reinforces an important maxim of clinical practice. “A concerned parent’s opinion can be disproved but must never be ignored”.

References

The Link between Estrogen and Serotonin

Lokuge S et al., (2011). Depression in women: windows of vulnerability and new insights into the link between estrogen and serotonin. The Journal of clinical psychiatry, 72(11), e1563-9.

Interactions of estrogen and insulin-like growth factor-I in the brain

Cardona-Gómez GP et al., Interactions of estrogen and insulin-like growth factor-I in the brain: molecular mechanisms and functional implications. The Journal of steroid biochemistry and molecular biology, 83(1), 211-217.

The link between Serotonin and Insulin

Paulmann N et al., (2009). Intracellular serotonin modulates insulin secretion from pancreatic β-cells by protein serotonylation. PLoS biology, 7(10),

Estrogen and Seizures

Velíšková J et al., (2010). Females, their estrogens, and seizures. Epilepsia, 51(s3), 141-144.

PCOS and Depression treatment

Rasgon, N., & Elman, S. When not to treat depression in PCOS with antidepressants.

Borderline personality disorder and polycystic ovary syndrome
Trisno, R., Worsley, R., & Kulkarni, J. (2015). Borderline personality disorder and polycystic ovary syndrome. Australian and New Zealand Journal of Psychiatry, 0004867415615950.