What Should Psychiatrists and Cardiologists Know About Depression and Cardiovascular Disease?
The ‘Broken Heart Syndrome’ was first reported in 1963 when widowers became depressed after spousal bereavement and subsequently had a high risk of mortality from heart disease a year after bereavement. The syndrome highlighted a possible link between Depression and Cardiovascular Disease (CVD) for the first time.
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Frasure-Smith, N., Lespérance, F., & Talajic, M. (1995). Depression and 18-month prognosis after myocardial infarction. Circulation, 91(4), 999-1005.